System for structural analysis of an object in order to produce a three-dimensional reconstruction of a structure of a portion of the object analyzed according to at least one three-dimensional reconstruction method, including means for generating an input light beam, arranged so as to cause the input beam generated to interact with at least the portion of the object, and means for receiving an output light beam resulting from interaction between the input beam and the object, the receiving means including a wavefront analyser arranged so as to measure an electromagnetic field of a wave of the output beam received, and the generating means having a spatial and/or temporal coherence adapted to that of the receiving means by spatial filtering means and/or spectral filtering systems, and the generating means and the receiving means being arranged, with respect to the object, so as to obtain a plurality of successive measurements of the output light beam resulting from the interaction between the input beam and the object according to a plurality of orientations of this interaction, with the generating means having a spatial and/or temporal coherence also adapted to the three-dimensional reconstruction method used.