Loading patent…
AssigneeSol-Gel Technologies Ltd.
InventorsOfer TOLEDANO, Hanan SERTCHOOK, Natalia LOBODA, Haim BAR-SIMANTOV, Leora SHAPIRO, Raed ABU-REZIQ
Estimating the term…
The invention relates to a composition for topical application comprising as an active ingredient a peroxide and a retinoid wherein one of said peroxide and retinoid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said peroxide and retinoid is present in an uncoated free form or in a coated form of the active ingredient. The invention further relates to method for treating a surface condition in a subject using said composition, a method for preparing a composition exhibiting improved stability, and a kit comprising: (a) a first composition comprising a peroxide as a first active ingredient; and (b) a second composition comprising a retinoid as a second active ingredient; at least one of said first and said second active ingredient being coated by a metal oxide layer.
A composition for topical application comprising as an active ingredient a peroxide and a retinoid wherein one of said peroxide and retinoid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said peroxide and retinoid is present in an uncoated free form or in a coated form of the active ingredient.
A composition for topical application comprising as an active ingredient benzoyl peroxide and all trans retinoic acid wherein one of said benzoyl peroxide and all trans retinoic acid is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said benzoyl peroxide and all trans retinoic acid is present in an uncoated free form or in a coated form of the active ingredient.
A composition for topical application comprising as an active ingredient benzoyl peroxide and tazarotene wherein one of said benzoyl peroxide and tazarotene is in the form of first microparticles comprising a solid particulate matter of the active ingredient coated by a metal oxide layer and the other of said benzoyl peroxide and tazarotene is present in an uncoated free form or in a coated form of the active ingredient.
A method for preparing a composition comprising as active ingredients a peroxide and a retinoid which are chemically unstable when formulated together, wherein the composition exhibits improved stability of at least one of the active ingredients, the method comprising:
A kit comprising:
Dependencies are inferred from the claim text.