Solid state forms of rasagiline salts
AssigneeActavis Group Ptc Ehf
InventorsNilesh Sudhir Patil, Haushabhau Shivaji Pagire, Neela Praveen Kumar, Nitin Sharadchandra Pradhan
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Abstract
Provided herein are novel crystalline forms of rasagiline salts, processes for their preparation, pharmaceutical compositions, and method of treating thereof. The rasagiline salts include a maleate salt, a mandelate salt, or a salicylate salt.
Claims17
Solid state form of a rasagiline salt, wherein the salt of rasagiline is a mandelate salt, a salicylate salt, or a rasagiline maleate salt crystalline Form II.
A pharmaceutical composition comprising solid state form of a rasagiline salt and one or more pharmaceutically acceptable excipients, wherein the solid state form of rasagiline salt is a rasagiline maleate crystalline Form II, a rasagiline mandelate crystalline Form I, or a rasagiline salicylate crystalline Form I.
A method for treating a patient suffering from diseases caused by brain ischemia, a neurotoxic injury, head trauma injury, spinal trauma injury, symptoms of withdrawal from an addictive substance, or structural damage of the optic nerve;
- comprising administering a pharmaceutical composition comprising the solid state form of a rasagiline salt along with pharmaceutically acceptable excipients, wherein the solid state form of rasagiline salt is a rasagiline maleate crystalline Form II, a rasagiline mandelate crystalline Form I, or a rasagiline salicylate crystalline Form I.
Dependencies are inferred from the claim text.