Mesenchymal stromal cell populations and methods of using same
AssigneeAllocure, Inc.
InventorChristof Westenfelder
Life of this patent
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Abstract
The invention relates to mesenchymal stromal cells produced by culturing the cells in platelet lysate supplemented media and methods of using these cells to treat neurological and kidney associated disorders.
Claims17
A method of treating or decreasing the likelihood of onset of a renal disorder associated with surgery in a subject in need by administering a therapeutically effective dose of a population of mesenchymal stromal cells (MSC) isolated by the method comprising:
- (a) providing bone marrow;
- (b) culturing the bone marrow on tissue culture plates in culture media between 2 and 10 days;
- (c) harvesting non-adherent cells;
- (d) culturing the adherent cells between 9 and 20 days in platelet lysate supplemented media;
- and
- (e) removing the adherent cells from the tissue culture plates;
- thereby treating or decreasing the likelihood of onset of the renal disorder associated with surgery.
A method of treating or decreasing the likelihood of onset of a renal disorder associated with surgery in a subject in need by administering a therapeutically effective dose of a population of allogeneic mesenchymal stromal cells (MSC) thereby or decreasing the likelihood of onset of treating the renal disorder associated with surgery.
Dependencies are inferred from the claim text.