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US 2012/0269727 A1Published application
Imaging agents with improved pharmacokinetic profiles
AssigneeGe Healthcare Limited
InventorsALAN CUTHBERTSON, MAGNE SOLBAKKEN
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Abstract
The invention relates to compounds suitable for use in an imaging agent said imaging agent showing an improved pharmacokinetic profile.
Claims26
A compound comprising
- i) a PEG containing moiety comprising 2 to 30 ethylene glycol units;
- ii) an imageable moiety useful in PET imaging or SPECT imaging;
- and
- a hydrophobic non-peptidic vector moiety not having affinity for the Angiotensin II receptor for delivery of said compound to a disease associated target.
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A compound comprising
- i) a PEG containing moiety comprising 2 to 30 ethylene glycol units;
- ii) an imageable moiety useful in PET imaging or SPECT imaging;
- and
- iii) a hydrophobic non-peptidic vector moiety for delivery of said compound to a disease associated target.
1 more element
A compound comprising:
- i) a PEG-containing moiety comprising 2 to 30 ethylene glycol units;
- ii) an imageable moiety;
- and
- iii) a hydrophobic non-peptidic vector moiety for delivery of said compound to a disease associated target.
1 more element
Dependencies are inferred from the claim text.