Delivery systems for brachytherapy, and associated methods
AssigneeThe University of North Carolina at Chapel Hill
InventorsZhuang Wang, Michael Edward Werner, James Donald Byrne, Ronald Chingyun Chen, Shrirang Shrikant Karve, Joseph DeSimone
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Abstract
Delivery systems adapted for implementation during a brachytherapy procedure are provided. The delivery system includes a plurality of brachytherapy seeds and a plurality of spacers. Each spacer is formed of a matrix material carrying a plurality of microparticles and/or nanoparticles. The microparticles and/or nanoparticles carry an agent and are biodegradable and/or biocompatible. The brachytherapy seeds and the spacers are configured to be delivered to a target site. Associated methods are also provided.
Claims30
A delivery system adapted for implementation during a brachytherapy procedure, the delivery system comprising:
- a plurality of brachytherapy seeds;
- and
- a plurality of spacers, each spacer comprising a matrix material carrying at least one of a plurality of microparticles or nanoparticles, the at least one of the microparticles or nanoparticles carrying at least one agent and being at least one of biodegradable or biocompatible,
- wherein the brachytherapy seeds and the spacers are configured to be delivered to a target site.
A method for co-delivery of an agent during a brachytherapy procedure, the method comprising:
- delivering a plurality of brachytherapy seeds proximate to a target site;
- and
- delivering a plurality of spacers proximate to the target site, each spacer comprising a matrix material carried by at least one of a plurality of microparticles or nanoparticles, the at least one of the microparticles or nanoparticles carrying at least one agent and being at least one of biodegradable or biocompatible.
Dependencies are inferred from the claim text.