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US 2012/0259128 A1Published application
Adamantanamine derivative
AssigneeShionogi & Co., Ltd.
InventorsTomoyuki Ogawa, Koji Masuda
Life of this patent
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Abstract
Disclosed is an adamantanamine derivative which is useful as a significant intermediate of an 11βHSD-1 inhibitor. Disclosed is a compound represented by the formula (II): wherein R10 is a group represented by the formula: —(CR13R14)m-NR12—R11 or the like.
Claims11
A compound represented by the formula (II):
- its salt, or a solvate thereof,
- wherein
- R10 is a group represented by the formula:
- —(CR13R14)m-NR12—R11,
- wherein R11 is substituted or unsubstituted acyl, substituted or unsubstituted alkylsulfonyl, substituted or unsubstituted alkyloxycarbonyl, substituted or unsubstituted carbamoyl or substituted or unsubstituted sulfamoyl, R12 is hydrogen or substituted or unsubstituted alkyl, R13 and R14 are each independently hydrogen, substituted or unsubstituted alkyl or halogen, m is an integer of 0 to 3 or
- a group represented by the formula:
- —(CR13R14)m-O—C(O)—NR15—R16,
- wherein R15 and R16 are each independently hydrogen or substituted or unsubstituted alkyl, R13, R14 and m are as defined above.
5 more elements
Dependencies are inferred from the claim text.