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US 2012/0259123 A1Published application
Aminopyridine compound
AssigneeUbe Industries, Ltd.
InventorsRyo Iwamura, Masayuki Tanaka, Tetsushi Katsube, Nobuhiko Shibakawa, Manabu Shigetomi, Eiji Okanari, Tomoko Kanda, Yasunori Tokunaga, Hiroshi Fujiwara
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Abstract
The present invention relates to a compound represented by the formula (I): or a pharmaceutically acceptable salt thereof, a medical composition containing the same, and a medical composition for the treatment or prophylaxis of respiratory diseases or glaucoma.
Claims21
An aminopyridine compound represented by the formula (I):
- wherein
- R1, R2 and R3 are each independently represent a hydrogen atom or a C1-C6 alkyl group,
- Y represents a formula (II):
- wherein Ring A represents an aromatic ring group or a 5- to 6-membered heteroaromatic ring group, R4 represents a C1-C12 alkyl group, a halogeno-C1-C8 alkyl group, a C1-C6 alkoxy group, a halogeno-C1-C6 alkoxy group, a halogeno-C1-C6 alkoxy-C1-C6 alkyl group, a C3-C6 cycloalkyl-C1-C6 alkyl group, a C2-C6 alkenyl group or the formula (III):
- wherein R6 represents a C1-C12 alkyl group, a C1-C6 alkoxy group, a C7-C18 aralkyl group, a C1-C6 alkoxy-C1-C6 alkyl group or a C7-C18 aralkyloxy-C1-C6 alkyl group, and n is an integer of 1 to 4, p is an integer of 1 to 3, R5 represents a halogeno group or an amino group which may be substituted by a C1-C6 alkyl group, and q is an integer of 0 to 2,
- Z represents an aromatic ring group or a 5- to 6-membered heteroaromatic ring group each of which may be substituted by a group(s) selected from the group consisting of a halogeno group, a C1-C6 alkyl group, a halogeno-C1-C6 alkyl group, a C1-C6 alkoxy group and a halogeno-C1-C6 alkoxy group,
- or a pharmaceutically acceptable salt thereof.
4 more elements
Dependencies are inferred from the claim text.