Association Between Ferroquine and an Artemisinine Derivative for Treating Malaria
AssigneeSanofi-Aventis
InventorsLaurent FRAISSE, Daniel TER-MINASSIAN
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Abstract
This invention is directed to methods for the treatment and prevention of malaria comprising administering a combination of ferroquine, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and an artemisinin derivative, and to pharmaceutical compositions comprising such combination.
Claims21
A method for the treatment of malaria in a patient in need thereof, comprising administering to such patient a therapeutically effective amount of a combination of ferroquine, in the form of a free base or a pharmaceutically acceptable salt thereof, and an artemisinin derivative.
A pharmaceutical composition comprising a therapeutically effective dose of ferroquine, or a pharmaceutically acceptable salt thereof, and a therapeutically effective amount of at least one artemisinin derivative, and at least one pharmaceutically acceptable excipient.
A pharmaceutical composition comprising a therapeutically effective dose of a combination of ferroquine, or a pharmaceutically acceptable salt thereof, and at least one artemisinin derivative, and at least one pharmaceutically acceptable excipient.
A kit for the treatment or of malaria, comprising, firstly, ferroquine or a pharmaceutically acceptable salt thereof and, secondly, at least one artemisinin derivative, said ferroquine and said artemisinin derivative being in distinct compartments and being intended to be administered simultaneously or sequentially.
Dependencies are inferred from the claim text.