Combination of polychitosamine and hmg-coa reductase inhibitor for hyperlipidemia
OwnerAndré Aubé, Jean-Guy Lehoux +2inventors
InventorsANDRÉ AUBÉ, Jean-Guy Lehoux, Ryszard Brzezinski, Gilles Dupuis
Life of this patent
Estimating the term…
Abstract
Combinations of therapeutic compounds for prophylaxis or treatment of hyperlipidemia and hyperlipidemia related disorders, such as hypercholesterolemia and the resultant atherosclerosis in a mammal. The combinations are useful for reducing serum cholesterol, and/or cholesteryl ester, triglycerides, phospholipids and fatty acids in a mammal. The methods of the preferred embodiments comprise administering to a mammal a first amount of polychitosamine and a second amount of an HMG-CoA reductase inhibitor (statin).
Claims46
A pharmaceutical composition comprising:
- a) an HMG-CoA reductase inhibitor;
- and
- b) a polychitosamine.
A method for the prophylaxis or treatment of hyperlipidemia or hyperlipidemia-associated condition comprising administering to said patient:
- a) a first amount of a polychitosamine;
- and
- b) a second amount of an HMG-CoA reductase inhibitor;
- wherein the first and second amounts together comprise a therapeutically effective amount.
A kit for the prophylaxis or treatment of hyperlipidemia or hyperlipidemia-associated condition in a mammal comprising a plurality of daily doses of dosage forms of an HMG-CoA reductase inhibitor, a plurality of daily doses of dosage forms of a polychitosamine together, and treatment regimen instructions.
Dependencies are inferred from the claim text.