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US 2012/0258909 A1Published application
Solid Compositions
AssigneeAbbott Laboratories
InventorsBernd Liepold, Tina Jung, Peter Hölig, Rudolf Schroeder, Nancy E. Sever, Justin S. Lafountaine, Brent D. Sinclair, Yi Gao, Jianwei Wu
Life of this patent
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Abstract
The present invention features solid compositions comprising amorphous Compound I. For instance, Compound I may be formulated in an amorphous solid dispersion which comprises a pharmaceutically acceptable hydrophilic polymer and preferably a pharmaceutically acceptable surfactant.
Claims19
A solid composition comprising
- (1) dimethyl(2S,2′S)-1,1′-((2S,2′S)-2,2′-(4,4′-((2S,5S)-1-(4-tert-butylphenyl)pyrrolidine-2,5-diyl)bis(4,1-phenylene))bis(azanediyl)bis(oxomethylene)bis(pyrrolidine-2,1-diyl))bis(3-methyl-1-oxobutane-2,1-diyl)dicarbamate
- or a pharmaceutically acceptable salt thereof, in an amorphous form;
- (2) a pharmaceutically acceptable hydrophilic polymer;
- and
- (3) a pharmaceutically acceptable surfactant.
2 more elements
Dependencies are inferred from the claim text.