Measuring chemical properties of a sample fluid in dialysis systems
AssigneeFresenius Medical Care Holdings, Inc.
InventorsStephen R. Ash, Thomas A. Sullivan, David Carr, Michael James Beiriger
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Abstract
In one aspect of the invention, a method includes determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system, determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate, and calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.
Claims47
A method comprising:
- determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system;
- determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate;
- and
- calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.
A method comprising:
- extracting a first portion of fluid from a fluid circuit of a dialysis system;
- causing the first portion of fluid to flow through a first channel into a first chamber that contains a composition to liberate a first CO2 gas from the first portion of fluid;
- determining a level of total CO2 in the first portion of fluid based at least in part on the first CO2 gas;
- extracting a second portion of fluid from the fluid circuit of the dialysis system;
- causing the second portion of the first portion of fluid to flow through a second channel into a second chamber to liberate a second CO2 gas from the second portion of fluid;
- and
- determining a level of total urea in the second portion of fluid based at least in part on the second CO2 gas.
A dialysis system comprising:
- a dialysis machine comprising a pH sensor and a CO2 sensor;
- and
- a dialysis fluid chamber configured to be connected to the dialysis machine, the dialysis fluid chamber comprising
- a housing defining an inlet port, an outlet port, a dialysis fluid passage extending between the inlet and outlet ports, and first and second apertures adjacent the fluid passage,
- a pH reactive material disposed over the first aperture of the housing;
- and
- a gas-permeable membrane disposed over the second aperture of the housing,
- wherein the pH reactive material and the gas-permeable membrane align with the pH sensor and CO2 sensor, respectively, when the dialysis fluid chamber is connected to the dialysis machine such that the pH sensor and CO2 sensor can be used to detect a pH level and CO2 level, respectively, of a dialysis fluid flowing through the dialysis fluid chamber.
A dialysis fluid chamber comprising
- a housing defining an inlet port, an outlet port, a dialysis fluid passage extending between the inlet and outlet ports, and first and second apertures adjacent the fluid passage,
- a pH reactive material disposed over the first aperture of the housing;
- and
- a gas-permeable membrane disposed over the second aperture of the housing,
- wherein the dialysis fluid chamber is configured such that the pH reactive material and the gas-permeable membrane align with a pH sensor and CO2 sensor, respectively, of a dialysis machine when the dialysis fluid chamber is connected to the dialysis machine.
A dialysis system comprising:
- a dialysis machine comprising a sensor;
- and
- a gas emission device configured to be connected to the dialysis machine in a manner such that dialysis fluid can be forced into the gas emission device, the gas emission device comprising:
- a housing defining first and second chambers;
- and
- a member defining a first fluid passage leading to the first chamber and a second fluid passage leading to the second chamber, at least one of the first and second fluid passages being heated such that dialysis fluid flowing along the at least one of the first and second fluid passages is heated to a desired temperature;
- wherein the first chamber contains an acid that causes CO2 to be emitted from dialysis fluid that is delivered to the first chamber via the first fluid passage, the second chamber can cause a gas to be emitted from dialysis fluid that is delivered to the second chamber via the second fluid passage, and the sensor is configured to detect an amount of CO2 emitted from the dialysis fluid delivered to the first chamber and to detect an amount of the gas emitted from the dialysis fluid delivered to the second chamber.
A gas emission device configured to be connected to a dialysis machine in a manner such that dialysis fluid can be forced into the gas emission device, the gas emission device comprising:
- a housing defining first and second chambers, and
- a member defining a first fluid passage leading to the first chamber and a second fluid passage leading to the second chamber, at least one of the first and second fluid passages being heated such that dialysis fluid flowing along the at least one of the first and second fluid passages is heated to a desired temperature,
- wherein the first chamber contains an acid that causes CO2 to be emitted from dialysis fluid that is delivered to the first chamber via the first fluid passage, the second chamber can cause a gas to be emitted from dialysis fluid that is delivered to the second chamber via the second fluid passage, and the gas emission device defines a flute portion that is positioned adjacent a sensor of the dialysis machine when the gas emission device is connected to the dialysis machine.
A method comprising:
- extracting a first portion of fluid from a fluid circuit of a dialysis system;
- causing the first portion of fluid to flow through a first channel into a first chamber that contains a composition to liberate a CO2 gas from the first portion of fluid;
- determining a level of total CO2 in the first portion of fluid based at least in part on the CO2 gas;
- extracting a second portion of fluid from the fluid circuit of the dialysis system;
- causing the second portion of the first portion of fluid to flow through a second channel into a second chamber to liberate a NH3 gas from the second portion of fluid;
- and
- determining a level of total urea in the second portion of fluid based at least in part on the NH3 gas.
Dependencies are inferred from the claim text.