Method for detecting and quantifying a target molecule in a sample
AssigneeImabiotech
InventorsJONATHAN STAUBER, Fabien Pamelard, David Bonnel, Grégory Hamm
Life of this patent
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Abstract
The invention relates to a method for identifying and quantifying by mass spectrometry at least one target molecule in a sample, comprising the following steps: a) depositing the sample to be analyzed on a support; b) analyzing the sample by mass spectrometry, so as to obtain the mass spectrum of the target molecule in said sample; c) weighting a signal associated with the mass spectrum of the target molecule in said sample by a extinction coefficient (TEC) specific to the target molecule and to the sample; and d) using the weighted signal of the target molecule to determine the quantity of target molecule in the sample.
Claims20
A method for detecting and quantifying by mass spectrometry at least one target molecule in a sample, comprising the following steps:
- a) depositing the sample to be analyzed on a support;
- b) analyzing the sample by mass spectrometry, so as to obtain the mass spectrum of the target molecule in said sample;
- c) weighting a signal associated with the mass spectrum of the target molecule in said sample by a extinction coefficient (TEC) specific to the target molecule and to the sample;
- and
- d) using the weighted signal of the target molecule to determine the quantity of target molecule in the sample.
Dependencies are inferred from the claim text.