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US 2012/0258472 A1Published application
Systems and methods of fluidic sample processing
AssigneeTheranos, Inc.
InventorsShaunak Roy, Malissa Takahashi, Ian Gibbons, Edmond Ku, Thanh Dang, Tammy Burd, Adam Vollmer, Elizabeth A. Holmes
Life of this patent
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Abstract
The present invention provides fluidic devices and systems that allow detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
Claims13
-26. (canceled)
A method of detecting an analyte in a bodily fluid from a subject, comprising:
- a) providing a fluidic device comprising a sample collection unit, an assay assembly, and a calibration unit, wherein,
- i) said sample collection unit is configured to a collect a sample of the bodily fluid from said subject;
- ii) said assay assembly comprises at least one reaction site containing a reactant configured to react with said analyte to yield a detectable signal indicative of the presence of said analyte;
- and
- iii) said calibration unit is configured to provide a measurement of said sample used for calibrating said detectable signal;
- b) allowing a portion of said sample to react with assay reagents contained within said assay assembly to yield a signal indicative of the presence of said analyte in said sample;
- and
- c) detecting said signal generated from said analyte collected in said sample of bodily fluid.
5 more elements
A method of measuring plasma concentration of a blood sample, comprising:
- a) providing a plasma sample substantially free of removing red blood cells;
- b) passing a current through said plasma sample;
- and
- c) measuring at least one of conductivity or impedance of said plasma sample, thereby measuring the plasma concentration of said blood sample.
1 more element
-48. (canceled)
Dependencies are inferred from the claim text.