Composition comprising fesoterodine and fiber
Assigneeratiopharm GmbH
InventorsDaniela Stumm, Katrin Rimkus
Life of this patent
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Abstract
The invention relates to a pharmaceutical composition containing (a) fesoterodine and/or fesoterodine metabolites and (b) fibers, wherein the weight ratio of components (a):(b) is in the range from 1:50 to 1:2; and oral dosage forms containing the pharmaceutical composition. The invention further relates to dry methods of preparing those dosage forms.
Claims17
A pharmaceutical composition comprising
- (a) fesoterodine and/or fesoterodine metabolites and
- (b) fibers,
- wherein the weight ratio of components (a):(b) is in the range from 1:50 to 1:2.
A method of preparing tablets, comprising the steps of:
- (i) mixing
- (a) fesoterodine and/or fesoterodine metabolites, and
- (b) fibers, with pharmaceutical excipients,
- and optionally further pharmaceutical excipients to form a mixture,
- (ii) compressing the mixture into tablets, optionally with the addition of further pharmaceutical excipients, and
- (iii) optionally film-coating the tablets.
A method for preparing a pharmaceutical formulation with modified release for the treatment of an overactive bladder, comprising the use if vegetable fibers, selected from alginates, gelatine, agar, gum arabic, gum tragacanth, xanthan and carrageenan.
Dependencies are inferred from the claim text.