Vaccine peptides
OwnerSimon Paul GRAHAMinventor
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Abstract
There is provided a polypeptide having an amino acid sequence selected from SEQ ID NOs:1, 2 and 3 or a functional fragment thereof, or comprising an amino acid sequence at least 65% identical to any one of SEQ ID NOs:1, 2 or 3. There is also provided a method of rapidly vaccinating an animal against infection by a pestivirus comprising administering to the animal an effective amount of a polypeptide comprising an E2 epitope polypeptide and/or an NS3 epitope polypeptide; the E2 epitope polypeptide may be SEQ ID NO:1 and the NS3 epitope polypeptide may be SEQ ID NO:2 or 3, or functional fragments thereof.
Claims22
An isolated polypeptide comprising an amino acid sequence of any one of SEQ ID NOs:1, 2 and 3 or a functional fragment thereof, or comprising an amino acid sequence at least 65% identical to any one of SEQ ID NOs:1, 2 or 3.
A method of rapidly vaccinating an animal against infection by a pestivirus comprising administering to the animal an effective amount of a polypeptide comprising an E2 epitope polypeptide and/or an NS3 epitope polypeptide.
A method of determining whether an animal has been exposed to infection by a pestivirus comprising contacting a sample of cells with a polypeptide comprising an E2 epitope polypeptide and/or an NS3 epitope polypeptide and determining whether levels of IFN-γ are increased in said cells after the contacting, an increase in IFN-γ levels being indicative of exposure of the animal to the virus.
Dependencies are inferred from the claim text.