Compositions and methods for the systemic treatment of arthritis
AssigneeBaylor Research Institute
InventorsJacques Banchereau, Virginia Pascual
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Abstract
The present invention includes compositions and methods for treating arthritic joints found in patients with auto-inflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks IL-1β receptors.
Claims8
A method for treating a joint with systemic onset juvenile idiopathic arthritis comprising administering to the joint a composition comprising a therapeutically effective amount of one or more active agents that reduces the bioavailability of interleukin-1 β by blocking one or more IL-1β receptors.
A method for treating a patient with systemic onset juvenile idiopathic arthritis comprising administering to the patient a composition comprising an effective amount of at least one agent capable of reducing or blocking the bioavailability of an interleukin-1β by blocking one or more IL-1β receptors.
Dependencies are inferred from the claim text.