Optical Blood Coagulation Monitor and Method
AssigneeSpectral Sciences, Inc.
InventorsBrian Gregor, Rama Bansil, Julian D. Spring
Life of this patent
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Abstract
An optical blood coagulation monitor and method. The monitor has a blood sample holder, a laser with its output light directed through the blood sample, a two-dimensional detector that is able to detect light at the laser light wavelength and that has a detector output, optics for imaging onto the detector laser light that is forward scattered by the blood, and a data analysis system, responsive to the detector output, that is adapted to analyze the detected light to provide information on time-resolved coagulation and clotting properties of the blood.
Claims21
A method of determining properties of blood, comprising:
- providing a blood sample;
- providing a laser and directing light from the laser through the blood sample;
- detecting over a period of time laser light that is forward scattered by the blood;
- and
- analyzing the detected light to provide information on time-resolved coagulation and clotting properties of the blood.
An optical blood coagulation monitor, comprising:
- a blood sample holder;
- a laser with its output light directed through the blood sample;
- a two-dimensional detector that is able to detect light at the laser light wavelength and that has a detector output;
- optics for imaging onto the detector laser light that is forward scattered by the blood;
- and
- a data analysis system, responsive to the detector output, that is adapted to analyze the detected light over time, to provide information on time-resolved coagulation and clotting properties of the blood.
An optical blood coagulation monitor, comprising:
- a blood sample holder;
- a laser with its output light directed through the blood sample, wherein the wavelength of the laser is in the visible to near infrared range;
- a two-dimensional detector that is able to detect light at the laser light wavelength and that has a detector output;
- optics for imaging onto the detector laser light that is forward scattered by the blood;
- and
- a data analysis system, responsive to the detector output, that is adapted to analyze the detected light over time, to provide information on time-resolved coagulation and clotting properties of the blood, wherein the provided information comprises the time for a clot to start forming, the rate of clot formation, and the strength of the clot;
- wherein the data analysis system samples a single laser speckle or a plurality of speckles over time, and determines the time dependent behavior of the time-based detected laser intensity via the analysis methods of photon correlation spectroscopy.
Dependencies are inferred from the claim text.