Devices and Methods for Tissue Engineering
AssigneeBio2 Technologies, Inc.
InventorJames Jenq Liu
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Abstract
A tissue scaffold fabricated from tantalum fiber forms a rigid three-dimensional porous matrix having a tantalum composition. Porosity in the form of interconnected pore space is provided by the space between the tantalum fiber in the porous matrix. Strength of the porous matrix is provided by tantalum fiber fused and bonded into the rigid three-dimensional matrix having a specific pore size and pore size distribution. The tissue scaffold supports tissue in-growth to provide osteoconductivity as a tissue scaffold, used for the repair of damaged and/or diseased bone tissue.
Claims18
A porous tissue scaffold comprising:
- tantalum fibers bonded together to provide a rigid three-dimensional matrix;
- interconnected pore space in the rigid three-dimensional matrix, the interconnected pore space having a pore size distribution predetermined by volatile components present before the tantalum fibers are bonded together;
- and
- the rigid three-dimensional matrix forming a porous tissue scaffold having a tantalum composition.
A porous tissue scaffold comprising:
- fibers in an intertangled relationship, the fibers having a tantalum composition;
- a tantalum material forming bonds between overlapping and adjacent fibers;
- the fibers and tantalum material providing a rigid three-dimensional matrix;
- interconnected pore space in the rigid three-dimensional matrix, the interconnected pore space having a pore size distribution predetermined by volatile components;
- and
- the rigid three-dimensional matrix forming a porous tissue scaffold.
A method of forming a porous tissue scaffold comprising:
- mixing tantalum fiber with binder, a pore former, and a liquid to provide a homogeneous mixture;
- forming the homogeneous mixture into a shaped object;
- curing the shaped object into the tissue scaffold;
- and
- applying a functional material to the tissue scaffold.
Dependencies are inferred from the claim text.