Stents including poly(l-lactide) formulations that minimize molecular weight drop during processing
AssigneeAbbott Cardiovascular Systems Inc.
InventorsByron Lambert, Yunbing Wang, James Oberhauser
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Abstract
A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
Claims27
A stent comprising a stent scaffolding, the stent scaffolding including a polymer formulation including poly(L-lactide) and polymandelide.
A stent comprising a stent scaffolding, the stent scaffolding comprising:
- a polymer formulation including poly(L-lactide) and polymandelide;
- and
- one or more stabilizing agents incorporated in the scaffolding, wherein the one or more stabilizing agents reduce the molecular weight reduction of the poly(L-lactide) upon its exposure to radiation, wherein the stabilizing agents are selected from the group consisting of a free radical scavenger, an oxygen scavenger, and a dessicant.
A medical device system comprising:
- a sealed package;
- a stent scaffolding disposed within the sealed package, wherein the scaffolding comprises a polymer formulation including poly(L-lactide) and polymandelide;
- and
- one or more stabilizing agents within the sealed package, wherein the one or more stabilizing agents reduce the molecular weight reduction of the poly(L-lactide) upon its exposure to radiation, wherein the stabilizing agents are selected from the group consisting of a free radical scavenger, an oxygen scavenger, and a dessicant.
Dependencies are inferred from the claim text.