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US 2012/0238938 A1Published application
Method and apparatus for the delivery of photo-chemical (cross-linking) treatment to corneal tissue
AssigneeSeros Medical, LLC
InventorsSatish V. HEREKAR, Edward E. MANCHE, Donald J. EATON
Life of this patent
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Abstract
Systems and methods for delivering and infusing formulations containing riboflavin or its analogues, or other ophthalmic formulations, into corneal tissue are disclosed. Systems and methods are further disclosed to cross-link the corneal tissue through exposure to UVA irradiation. The systems and methods for formulation delivery employ micro-needle array delivery devices.
Claims20
A method of treating ocular tissue comprising:
- providing a treatment apparatus comprising micro-needles;
- and
- delivering a drug formulation to corneal ocular tissue through penetration of micro-needles into the corneal ocular tissue, and
- wherein the drug formulation comprises riboflavin,
- wherein the delivered formulation is capable of inducing crosslinking of corneal collagen tissue upon exposure to irradiation.
2 more elements
A method of treating ocular tissue comprising:
- providing a UVA applicator;
- and
- delivering UVA irradiation from the UVA applicator to corneal ocular tissue exposed to a formulation comprising riboflavin, wherein the UVA irradiation crosslinks corneal collagen tissue exposed to the formulation.
A device for treating ocular tissue comprising:
- a micro-needle array disposed on a concave disk sized to fit over a corneal surface, wherein the micro-needles are configured to deliver formulation into a cornea upon penetration of the micro-needles into the corneal surface.
A device for treating ocular tissue comprising:
- a contact lens assembly comprising a contact lens that conforms to a corneal surface;
- a skirt around the contact lens configured to sit on a region of the sclera surrounding the cornea;
- and
- a UVA applicator associated with the contact lens assembly for providing UVA irradiation through the contact lens into the cornea.
1 more element
Dependencies are inferred from the claim text.