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US 2012/0238613 A1Published application
Sec-hydroxycyclohexyl derivatives
AssigneeHoffmann-La Roche Inc.
InventorsDaniel Hunziker, Werner Neidhart
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Abstract
The invention provides novel compounds having the general formula (I) wherein R1, R2 and R3 are as described herein, compositions including the compounds and methods of using the compounds.
Claims30
A compound according to formula (I),
- wherein
- R1 is selected from the group consisting of hydrogen, alkyl and cycloalkyl;
- R2 is selected from the group consisting of hydrogen, alkyl, cycloalkyl, cycloalkylalkyl, alkylcycloalkyl, alkylcycloalkylalkyl, alkoxy, alkoxyalkyl, cycloalkoxy, cycloalkoxyalkyl, haloalkyl, haloalkoxy, haloalkoxyalkyl, halocycloalkyl, halocycloalkylalkyl, halocycloalkoxy and halocycloalkoxyalkyl;
- and
- R3 is selected from the group consisting of phenyl, pyridinyl, pyrazinyl, pyrimidyl and pyridazinyl,
- wherein said phenyl, pyridinyl, pyrazinyl, pyrimidyl and pyridazinyl are optionally substituted with one to three substituents independently selected from the group consisting of alkyl, cycloalkyl, cycloalkylalkyl, halogen, haloalkyl, hydroxy, hydroxyalkyl, alkoxy, alkoxyalkyl, haloalkoxy, hydroxyhaloalkyl, alkoxyhaloalkyl and benzyloxyhaloalkyl;
- or a pharmaceutically acceptable salt thereof.
4 more elements
Dependencies are inferred from the claim text.