Derivatives of 7 alkynyl-1,8 naphthyridones, preparation method thereof and use of same in therapeutics

A method treating a disease selected from the group consisting of restenosis, nephrosclerosis, and liver cirrhosis, comprising administering to a patient in need thereof an effective dose of a compound of formula (I):

• wherein:
• R1 and R2 represent, independently of one another:
• a hydrogen atom, or
• a C1-C7 alkyl group optionally substituted by one or more alkoxy groups;
• R3 represents a C1-C7 alkyl group;
• R4 represents a hydrogen atom or a C1-C4 alkyl group;
• Y represents a C1-C4 alkoxy group or an —NRR′ or —O(CH2)n—C(O)—NRR′ group where R and R′ are as defined below and n is an integer equal to 1 or 2;
• R″ represents a C1-C4 alkyl group;
• and
• R and R′ represent, independently of one another, a hydrogen atom, a —CO—(C1-C4 alkyl) group or a —COOR″ group, where R″ is as defined above;
• or an acid addition salt thereof, or an enantiomer or diastereoisomer thereof, or a mixture thereof.