Formulations comprising palonosetron
AssigneeDr. Reddy's Laboratories, Inc.
InventorsChandrashekhar Kocherlakota, Sreedhar Bandari, Nagaraju Banda, Kranthi Kumar Hinge, Ramachandra Reddy Yeluri
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Abstract
Pharmaceutical compositions comprising palonosetron and its pharmaceutically acceptable salts, in the form of a ready-to-use solution or a lyophilized form. Specific embodiments of the invention relate to stable pharmaceutical formulations of palonosetron and its pharmaceutically acceptable salts, wherein the formulation does not comprise a chelating agent or an antioxidant.
Claims20
A pharmaceutical formulation for parenteral administration, comprising:
- a) palonosetron or a pharmaceutically acceptable salt thereof;
- and b) a pharmaceutically acceptable carrier;
- wherein the formulation is substantially fee of chelating agents, antioxidants, or both.
A lyophilized solid containing a pharmaceutically acceptable salt of palonosetron, a tonicity contributor, and a buffering agent.
Dependencies are inferred from the claim text.