Water-soluble polysaccharide ethers and their use
AssigneePharmpur GmbH
InventorsHelmut Ritter, Bernd Mueller, Dirk-Henning Menz
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AssigneePharmpur GmbH
InventorsHelmut Ritter, Bernd Mueller, Dirk-Henning Menz
Estimating the term…
The invention relates to modified polysaccharide ethers having a weight-averaged molecular weight of 40000 to 50000 g/mole, zero shear viscosity of more than 10 Pas, and pseudoplasticity of more than 20, obtainable by reacting cellulose-based polysaccharide ether(s) with at least one mesogenic modification agent or modified polysaccharide ethers, obtainable by reacting polysaccharide ether(s) selected from the group consisting of hydroxypropylmethyl cellulose (HPMC), hydroxyethylmethyl cellulose (HEMC), methyl cellulose, and cellulose ethers with methyl and/or ethyl and/or propyl groups and mixtures thereof, with at least one mesogenic modification agent. Said substances can be used to produce gel-like to stable aqueous preparations having viscoelastic flow properties, which are suited for use in the human body, particularly within the scope of ophthalmologic procedures.
Modified polysaccharide ethers with a weight-averaged molecular weight of 40,000-500,000 g/mol, a zero-shear viscosity of more than 10 Pa·s, and a pseudo-plasticity of more than 20, which can be obtained by a reaction of polysaccharide ether(s) based on cellulose with at least one mesogenic modification agent.
Modified polysaccharide ether, which can be obtained by a reaction of polysaccharide ether(s) selected from hydroxypropyl methylcellulose (HPMC), hydroxyethyl methylcellulose (HEMC), methylcellulose, cellulose ethers with methyl and/or ethyl and/or propyl groups and mixtures thereof with at least one mesogenic modification agent.
Dependencies are inferred from the claim text.