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US 2012/0238502 A1Published application
Anti-fibrotic hydrogel compositions
OwnerSebastianus Gerardus Kluijtmansinventor
Life of this patent
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Abstract
A cross linked recombinant gelatin composition for the controlled release of a cellular adhesion inhibitory agent.
Claims15
1-29. (canceled)
A composition comprising:
- (a) at least one cellular adhesion inhibitory agent wherein the cellular adhesion inhibitory agent(s) is/are selected from the group consisting of alginate, chondroitan sulfate, dermatan sulfate, dextran sulfate, hyaluronic acid, heparin, heparin sulfate, keratin sulfate, and pentose polysulfate;
- and
- (b) a cross-linked recombinant gelatin hydrogel matrix wherein the recombinant gelatin comprises at least 0.3 mmol/g lysine and/or hydroxylysine residues before cross-linking and at least 0.15 mmol/g free amine after cross-linking.
Dependencies are inferred from the claim text.