Immunologically active lipopeptides and methods for use thereof
AssigneeTherimunex Pharmaceuticals, Inc.
InventorJames Douglas Thacker
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Abstract
The present invention relates to the isolation and structure elucidation of 1-peptidyl-2-arachidonoyl-3-stearoyl glyceride (pDAG) as an active chemical entity in the caprine serum fraction, and the discovery of the innate immune modulating activity of pDAG as an endogenous damage associated molecular pattern
Claims6
A compound having the formula:
1-peptidyl-2-arachidonoyl-3-stearoyl glyceride.
A method for inducing inflammatory cytokine and chemokine production and release from human fibroblasts, which method comprises administering to said fibroblasts a physiologically effective dose of a compound having the formula:
A method for the treatment and mitigation of bacterial and viral infections in a subject, which method comprises administering to the subject a physiologically effective dose of a compound having the formula:
Dependencies are inferred from the claim text.