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US 2012/0238469 A1Published application
Diagnostic biomarker to identify women at risk for preterm delivery
AssigneeCedars-Sinai Medical Center
InventorsOzlem Equils, Charles F. Simmons
Life of this patent
Estimating the term…
Abstract
The invention relates to biomarkers associated with preterm delivery. More specifically, the invention provides methods of measuring biomarkers found in women that are at risk for preterm delivery.
Claims19
A method of identifying a non-pregnant woman at risk for preterm delivery, comprising:
- (a) obtaining a sample from the non-pregnant woman;
- (b) determining the expression level of one or more biomarkers in the sample;
- (c) comparing the expression level of the one or more biomarkers with the expression level of biomarkers from women who delivered fullterm;
- and
- (d) determining that the level of expression of at least one of each of the one or more biomarkers in the sample is higher or lower than the level of expression of the same biomarkers in the women who delivered fullterm.
2 more elements
A method of diagnosing susceptibility to preterm delivery in a woman, comprising:
- (a) obtaining a sample from the woman;
- (b) determining the expression level of one or more diagnostic biomarkers in the sample;
- (c) comparing the expression level of each of the one or more diagnostic biomarkers in the sample with the expression level of each of one or more of the same biomarkers from women who delivered fullterm;
- and
- (d) determining that the level of expression of at least one of each of the one or more diagnostic biomarkers in the sample is higher or lower than the level of expression of the same one or more diagnostic biomarkers in the women who delivered fullterm.
2 more elements
A kit, comprising:
- a biomarker assay;
- and
- instructions for the use of the assay for identifying a non-pregnant woman at risk for preterm delivery.
A kit, comprising:
- a diagnostic assay;
- and
- instructions for the use of the assay for diagnosing susceptibility of a woman to preterm delivery.
Dependencies are inferred from the claim text.