Method for determining the risk of occurrence of alzheimer's disease
AssigneesInstitut Pasteur de Lille, Commissariat A L'energie Atomique Et Aux Energies Alternatives, Institut National De La Sante Et De La Recherche Medicale (Inserm), Universite Lille 2 Droit Et Sante
InventorsPhilippe Amouyel, Mark Lathrop, Jean-Charles Lambert
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Abstract
The present invention relates to an in vitro method for determining that an individual is at risk of developing Alzheimer's disease, which comprises: —determining whether the individual harbours at least one variant allele of a susceptibility gene selected from the apolipoprotein J gene (APOJ) and the complement component receptor 1 gene (CR 1); —deducing that if the individual harbours at least one variant allele of the APOJ and/or CR1 gene, then the individual is at risk of developing Alzheimer's disease.
Claims12
An in vitro method for determining that an individual is at risk of developing Alzheimer's disease, which comprises:
- determining whether the individual harbours at least one variant allele of a susceptibility gene selected from the apolipoprotein J gene (APOJ) and the complement component receptor 1 gene (CR1);
- deducing that if the individual harbours at least one variant allele of the APOJ and/or CR1 gene then the individual is at risk of developing Alzheimer's disease.
Dependencies are inferred from the claim text.