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US 2012/0238011 A1Published application
Continuous recovery harvest bag
AssigneeXcellerex, Inc.
InventorsColin Tuohey, Thomas Erdenberger, Richard Damren, Michael Fisher, John Swibes
Life of this patent
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Abstract
Disclosed herein is a single use continuous recovery, flow-through harvest vessel and corresponding method for harvesting culture medium and simultaneously either leaving the microcarrier beads behind in the vessel or flowing microcarrier beads and medium back into a bioreactor.
Claims15
A nonporous vessel capable of holding a fluid, the vessel comprising:
- an outer wall surface and an inner wall surface, the inner wall surface defining an interior chamber for holding the fluid;
- a filter having a perimeter, a first surface and a second surface, and fixedly attached around its entire perimeter to a portion of the inner wall surface of the nonporous vessel, thereby forming an integrated interior bag within the nonporous vessel;
- and
- a first fitment attached to the outer wall surface of the nonporous vessel at a portion of the outer wall surface that is adjacent to the integrated interior bag, the first fitment forming a first port configured to allow fluid to flow from the interior chamber through the filter into the integrated interior bag, and out of the first port.
1 more element
A nonporous container having a first interior chamber capable of holding a fluid, the nonporous container comprising:
- an interior pouch having a second interior chamber and integral with a wall of the nonporous container, the interior pouch comprising a porous surface adjacent to the first interior chamber of the nonporous container and configured such that the first interior chamber and the second interior chamber are in fluid communication with one another;
- a fitment forming a port on a surface of the nonporous container, the port positioned to allow access to the second interior chamber, such that when the fluid contained in the first interior chamber is allowed to flow out of the port on the surface of the nonporous container, the fluid passes out of the first interior chamber and through the porous surface, forming a filtrate, the filtrate passing through the interior pouch, and out of the port.
Dependencies are inferred from the claim text.