Luminogen compounds and the use of the same for biosensing and cellular imaging
AssigneeThe Hong Kong University of Science and Technology
InventorsBenzhong TANG, Yang Liu, Wing Yip Lam, Yong Yu
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Abstract
Provided herein are a luminogen compound of formula (I) including a AIE luminophore moiety conjugated with a maleimide moiety and a use of the same for detecting thiol groups in biomolecules. Also provided is a dye molecule, a biosensor or a bioprobe comprising the luminogen compound of formula (I) in use for detecting thiol groups in biomolecules. The detection method of the present subject matter not only has high thio-selectivity and sensitivity, but also is rapid, convenient and handy.
Claims21
A conjugated luminogen compound comprising an aggregation-induced emission (AIE) luminophore moiety and a maleimide moiety, represented by the following formula (I):
- wherein R is an aggregation-induced emission (AIE) luminophore.
Dependencies are inferred from the claim text.