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US 2012/0237925 A1Published application
Portable Sample Disruptor Apparatus, Kits, and Methods
AssigneeZymo Research Corporation
InventorsNikolas M. Isely, Marc E. Van Eden, Jonathan K. Brown
Life of this patent
Estimating the term…
Abstract
Apparatuses, kits, and methods for portable sample disruption (e.g., for encouraging cell lysis).
Claims21
A apparatus comprising:
- a body defining a chamber having a first end and a second end configured to permit a container to be inserted into the chamber, the body configured to be coupled to a device having a piston such that the volume of the chamber can be varied by reciprocating the piston between a retracted position and an extended position;
- a cap configured to be coupled to the body such that the cap covers the second end of the chamber;
- where if the body is coupled to the device, the piston can be reciprocated to vibrate a container disposed in the chamber.
A method comprising:
- providing an apparatus comprising a body and a cap, the body defining a chamber having a first end and a second end, and the cap configured to be coupled to the body such that the cap covers the second end of the chamber;
- coupling the body to a device having a piston such that:
- the volume of the chamber can be varied by reciprocating the piston between a retracted position and an extended position;
- and
- the piston can be reciprocated to vibrate a container disposed in the chamber.
2 more elements
A method comprising:
- providing an apparatus comprising a body and a cap, the body defining a chamber having a first end and a second end, and the cap configured to be coupled to the body such that the cap covers the second end of the chamber, where the body is coupled to a device having a piston such that the volume of the chamber can be varied by reciprocating the piston between a retracted position and an extended position;
- disposing a container in the chamber;
- coupling the cap to the body;
- and
- activating the device to vibrate the container.
2 more elements
A method comprising:
- mechanically disrupting a cell sample disposed in a container such that nucleic acid is released from cells in the sample,
- where mechanically disrupting includes activating a battery-powered device of an apparatus to cause reciprocation of a piston to vibrate the container.
Dependencies are inferred from the claim text.