Viral Diagnostics
AssigneeBioscience Slovakia
InventorsJana Tomaskova, Juraj Kopacek, Jaromir Pastorek, Silvia Pastorekova
Life of this patent
Estimating the term…
Abstract
The present disclosure provides methods for determining whether a subject is infected with lymphocytic choriomeningitis virus (LCMV). These methods include obtaining a sample from a subject with increased susceptibility to LCMV infection, contacting the sample with one or more compositions for detecting LCMV, and determining whether the one or more compositions for detecting LCMV is associated with a marker of LCMV from the sample, wherein detection of an association indicates that that the subject is infected with LCMV.
Claims52
A method of assessing lymphocytic choriomeningitis virus (LCMV) infection status or activity in a subject, the method comprising:
- selecting a subject for assessment, wherein the subject has been exposed to LCMV and/or is at risk of increased LCMV activity;
- obtaining a sample from the subject:
- contacting the sample with at least one composition for detecting LCMV;
- and
- determining whether the at least one composition for detecting LCMV is associated with a marker of LCMV from the sample, wherein detection of an association indicates that that the subject is infected with and/or has active LCMV.
A diagnostic kit for assessing lymphocytic choriomeningitis virus (LCMV) infection status or activity in a sample, wherein the kit comprises:
- at least one primer that binds specifically to one or more LCMV nucleic acids;
- at least one LCMV protein or fragment thereof;
- at least one isolated LCMV binding antibody or antibody fragment;
- or
- any combination thereof.
Dependencies are inferred from the claim text.