Formulations, devices and methods for treating and preventing mucositis
AssigneeAccentia Biopharmaceuticals, Inc.
InventorsFRANCIS E. O'DONNELL, JR., ANGELOS M. STERGIOU
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Abstract
The present invention is directed to compositions, devices, and methods for non-irritatively treating and preventing mucositis, such as chronic rhinosinusitis (CRS). Some aspects of the invention concern compositions comprising or consisting essentially of sodium phosphate buffer (e.g., sodium phosphate dibasic and sodium phosphate monobasic) and calcium carbonate; mucoadministration devices and kits containing such compositions; and methods for treating or preventing mucositis conditions such as CRS, comprising mucoadministering a composition of the invention to a subject in need thereof.
Claims20
A composition comprising sodium phosphate buffer and calcium carbonate.
A mucoadministration device containing a composition comprising sodium phosphate buffer and calcium carbonate.
A kit for treating or preventing mucositis, comprising a pre-filled container containing a composition comprising sodium phosphate buffer and calcium carbonate, and at least one component selected from the group consisting of:
- a mucoadministration device, a mixing chamber, a diluent, and printed instructions for treating or preventing mucositis.
A method of treating or preventing mucositis in a subject in need thereof, comprising mucoadministering to the subject an effective amount of a composition comprising sodium phosphate buffer and calcium carbonate.
Dependencies are inferred from the claim text.