Endoplasmic reticulum targeting liposomes
AssigneeUniversity of Oxford
InventorsStephanie Pollock, Raymond Allen Dwek, Nicole Zitzmann
Life of this patent
Estimating the term…
Abstract
Provided are compositions that include lipid particles, such as liposomes, that can fuse with the ER membrane of a cell. The lipid particles can also deliver a cargo, such as a therapeutic or an imaging agent, encapsulated inside the particles inside the ER lumen of the cell. The compositions can be useful for treating and/or preventing diseases or conditions caused by or associated with a virus, such as viral infections, including HIV and HCV infections.
Claims32
1-106. (canceled)
A composition comprising (a) a lipid particle that comprises phosphatidylserine and (b) at least one antiviral agent encapsulated in the lipid particle, wherein the at least one antiviral agent comprises an alpha-glucosidase inhibitor, an iminosugar or an ion channel inhibitor.
Dependencies are inferred from the claim text.