Back to results
US 2012/0237589 A1Published application
Amphoteric liposomes comprising imino lipids
AssigneeMarina Biotech, Inc.
InventorsSteffen Panzner, Evgenios Siepi
Life of this patent
Estimating the term…
Abstract
The invention concerns lipid assemblies, liposomes having an outer surface comprising a mixture of anionic and cationic moieties; wherein at least a portion of the cationic moieties are imino moieties that are essentially charged under physiological conditions, and their use for serum resistant transfection of cells.
Claims23
Lipid assemblies comprising anionic and cationic amphiphiles;
- wherein at least a portion of the cationic amphiphiles are imino lipids that are substantially charged under physiological conditions, and wherein the anionic amphiphiles are carboxyl or phosphate lipids and wherein further the charge ratio between the cationic and anionic amphiphiles is 1.5 or less.
(canceled)
(canceled)
Dependencies are inferred from the claim text.