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AssigneeVenture Isles, LLC
InventorsTushar K. Ray, Clyde G. Hanson, Paul Burgio
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The present invention relates to improved methods of preventing or inhibiting the release of acid in the stomach, which are uniquely reversible at the cellular level, through the use of organic isothiocyanates and thiocyanates with divalent cations such as barium, zinc and calcium for human and veterinary applications. The present invention also relates to methods of preventing or treating persistent chronic gastritis, GERDs, ulcer and or stomach cancer by inhibiting the release of stomach acid and by reducing inflammation with fewer and milder side-effects expected than current treatments. A method of screening therapeutics is described.
A method of treating a subject that has an elevated level of stomach-acid secretion, inflammation, or cancer anywhere in the body by administering a composition to said subject where it is composed of one or more of a thiocyanate that has the structure of Formula (I)
A method of treating excess stomach acid, inflammation or cancer comprising a single or a combination of active ingredients contained in an oral delivery system extending the release of the clinically significant concentrations of the active ingredients and/or enhancing absorption into the bloodstream by releasing the active ingredients at two or more stages of the gastro-intestinal (GI) tract by the design of the delivery system, wherein the oral delivery system includes a first clinically in-active carrier material that facilitates dissolution and absorption of the first, second, or third layer in the stomach and a second clinically in-active carrier material that facilitates dissolution and absorption of the first, second, or third layer in the small or large intestine and a third clinically in-active carrier material that facilitates dissolution and absorption of the first, second or third layer in the large intestine.
Dependencies are inferred from the claim text.