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US 2012/0237544 A1Published application
Bacterial spore having therapeutic agent adsorbed on its surface
AssigneeRoyal Holloway and Bedford New College
InventorsSimon Michael Cutting, Hong Anh Huynh
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Abstract
The present invention relates to a method of coating a spore with one or more therapeutic agents. The present invention also relates to a coated spore obtained by the method of the present invention and the use of the coated spore as a vaccine.
Claims34
A method of adsorbing a therapeutic agent onto a bacterial spore comprising:
- mixing the spores and the therapeutic agent at a pH that is less than or equal to the isoelectric point of the therapeutic agent.
The method of any one of the preceding claims, wherein the spore is denatured so that germination is prevented.
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Dependencies are inferred from the claim text.