Diagnostic antibody assay
AssigneeProbiodrug AG
InventorsMartin Kleinschmidt, Stephan Schilling, Jens-Ulrich Rahfeld, Kristin Ebermann, Hans-Ulrich Demuth
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Abstract
Novel diagnostic assays for the diagnosis of amyloidosis, in particular Alzheimer's disease, and related aspects. In particular, monoclonal antibodies and an antibody assay are provided.
Claims29
An antibody that binds to AβpGlu(11) peptides or variants thereof, preferably with high affinity.
An antibody obtainable from the hybridoma cell line DSM ACC 3100.
A composition comprising an antibody that binds to AβpGlu(11) peptides or variants thereof, preferably with high affinity.
A method for the treatment, prevention or delay of amyloidosis comprising administering to a subject in need thereof a composition comprising an antibody that binds to AβpGlu(11) peptides or variants thereof, preferably with high affinity.
A hybridoma cell line DSM ACC 3100.
An oligonucleotide selected from the group consisting of SEQ ID NOs:
- 26 to 50.
Dependencies are inferred from the claim text.