Combination preparation including a cytokine antagonist and corticosteroid
AssigneeOrthogen AG
InventorsPeter Wehling, Julio Reinecke
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Abstract
The present invention relates to pharmaceutical compositions for a combination therapy with a cytokine antagonist and a corticosteroid. By means of the combination therapy diseases such as osteoarthritis, tendon injuries and/or degenerative spinal diseases can be treated.
Claims21
Pharmaceutical composition comprising a corticosteroid together with a cytokine antagonist and optionally a growth factor, wherein the cytokine antagonist is the naturally occurring or recombinant interleukin antagonist IL-1Ra protein, particularly Orthokine or Anakinra, and wherein the pharmaceutical composition is suitable for local administration.
Pharmaceutical composition comprising a cytokine antagonist and optionally a growth factor for use in a combination therapy together with a corticosteroid, wherein the cytokine antagonist is the naturally occurring or recombinant interleukin antagonist IL-1Ra protein, particularly Orthokine or Anakinra, and wherein the pharmaceutical composition is suitable for local administration.
Pharmaceutical composition comprising a corticosteroid for use in a combination therapy together with a cytokine antagonist and optionally a growth factor, wherein the cytokine antagonist is the naturally occurring or recombinant interleukin antagonist IL-1Ra protein, particularly Orthokine or Anakinra and wherein the pharmaceutical composition is suitable for local administration.
Kit comprising a pharmaceutical composition comprising a cytokine antagonist and optionally a growth factor and a pharmaceutical composition comprising a corticosteroid, wherein the cytokine antagonist is the naturally occurring or recombinant interleukin antagonist IL-1Ra protein, particularly Orthokine or Anakinra, and wherein the pharmaceutical compositions are suitable for local administration.
Use of a cytokine antagonist and optionally of a growth factor for the preparation of a pharmaceutical composition for use in a combination therapy together with a corticosteroid, wherein the cytokine antagonist is the naturally occurring or recombinant interleukin antagonist IL-1Ra protein, particularly Orthokine or Anakinra, and wherein the pharmaceutical composition is suitable for local administration.
Use of a corticosteroid for the preparation of a pharmaceutical composition for the use in a combination therapy together with a cytokine antagonist and optionally a growth factor, wherein the cytokine antagonist is the naturally occurring or recombinant interleukin antagonist IL-1Ra protein, particularly Orthokine or Anakinra, and wherein the pharmaceutical composition is suitable for local administration.
Dependencies are inferred from the claim text.