Oncolytic Virotherapy for Prevention of Tumor Recurrence
AssigneeRuprecht-Karls-Universitaet Heidelberg
InventorsJean Rommelaere, Zahari Raykov, Svitlana Grekova, Irina Kiprijanova, Karsten Geletneky, Ute Koch, Marc Aprahamian
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Abstract
Described is a parvovirus for preventing recurrence of a tumor, preferably a malignant brain tumor or pancreas tumor.
Claims7
-8. (canceled)
A method of preventing recurrence of tumors, comprising administering a parvovirus, wherein the parvovirus is H1 (HIPV).
The parvovirus according to claim 1, wherein said tumor is a brain tumor or pancreas tumor.
The parvovirus according to claim 2, wherein said brain tumor is glioma, medulloblastoma or meningioma.
The parvovirus according to claim 3, wherein said glioma is a malignant human glioblastoma.
The parvovirus according to claim 1, wherein said parvovirus is administered by intravenous (i.v.), intratumoral, intracranial or intracerebral administration.
A pharmaceutical composition for the prevention of recurrent tumors, comprising H1PV and pharmaceutically acceptable excipients thereof.
Dependencies are inferred from the claim text.