Methods for treatment of neurological disorders by modulation of microglial activation

A method of treating or ameliorating a neurological disorder comprising microglial activation, the method comprising:

• administering to an individual suffering from the condition:
• a probiotic dosage comprising a therapeutically effective probiotic amount;
• and
• an NSAID dosage comprising a therapeutically effective NSAID amount;
• wherein:
• the NSAID dosage is configured to inhibit a microglial activation in the individual;
• the probiotic dosage is configured to at least one of prevent or restrict gastrointestinal lesions resulting from the NSAID dosage;
• the probiotic dosage is of between approximately 200 billion CFUs to approximately 400 billion CFUs per day;
• and
• the NSAID dosage comprises at least one of:
• an ibuprofen dose of between approximately 60 mg/kg per day to approximately 90 mg/kg per day with respect to a weight of the individual;
• or
• a dexibuprofen dose of between approximately 33 mg/kg per day to approximately 51 mg/kg per day with respect to the weight of the individual.