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AssigneeBASF SE
InventorsBruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen
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The present invention relates to a microorganism belonging to the group of lactic acid bacteria capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; (ii) resistant to protease treatment; (iii) calcium-dependent; (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. The present invention is also relates to an analog or fragment of the microorganism which is thermally inactivated or lyophilized, wherein the analog or fragment retains the capability of specifically binding to Streptococcus mutans. The invention further encompasses compositions and additives for food, feed or drinks comprising the microorganism or an analog or fragment thereof. Also provided is uses of the microorganism or an analog or fragment thereof for the preparation of an anticariogenic or pharmaceutical composition or anticariogenic food or feedstuff as well as methods for producing the compositions or food or feedstuff.
An isolated microorganism belonging to the group of lactic acid bacteria, wherein said isolated microorganism binds to Streptococcus mutans in the presence of saliva or at a pH range between 4.5 and 8.5, and wherein the binding between said isolated microorganism and Streptococcus mutans is calcium-dependent, resistant to heat treatment at more than 95° C. for at least 20 minutes, or resistant to protease treatment.
An isolated microorganism belonging to the group of lactic acid bacteria isolated from an assay comprising:
Dependencies are inferred from the claim text.