Method for detecting bpa by surface enhanced raman spectroscopy

A Method for detecting BPA by Surface Enhanced Raman Spectroscopy, comprising:

• (1) soaking and ultrasonically extracting bisphenol A present in a sample with an organic solvent to form an extraction solution, adding methanol to the extraction solution to cause a polymer to precipitate from the extraction solution and leaving a filtrate behind, filtering and concentrating the filtrate, diluting the concentrated filtrate to volume with methanol, and filtering the diluted filtrate through a filter with a pore size of 0.45 μm to obtain a pretreated sample;
• (2) reducing KAuCl4 with sodium citrate to obtain colloidal gold with evenly-distributed particle sizes;
• (3) detecting bisphenol A present in the sample by Raman spectroscopy, wherein spectral conditions for Raman spectroscopy include an incident laser power of 100 to 300 mW, and a scan time of 2 to 20 seconds;
• and
• (4) mixing the pretreated sample obtained in step (1) with the colloidal gold obtained in step (2) in an appropriate ratio, followed by adjusting pH value with an acid or a base, and then carrying out the detection of bisphenol A present in the sample by Raman spectroscopy under the spectral conditions shown in step (3).