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US 2012/0234324 A1Published application
System for providing support therapy while determining concentrations of a molecular gaseous expired by a subject receiving pressure support therapy
AssigneeKoninklijke Philips Electronics N.V.
InventorJoseph Allen Orr
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Abstract
Pressure support therapy is provided to a subject. The effectiveness of the provided pressure support therapy is determined and/or the therapy is titrated based on determinations of the concentration of one or more gaseous molecular species in gas exhaled by the subject. The determinations of composition of gas exhaled by the subject are obtained from samples with relatively little distortion caused by dilution of expired gases from gases provided to the airway of the subject as part of the pressure support therapy.
Claims20
A pressure support system comprising:
- a pressure generator configured to generate a pressurized flow of breathable gas for delivery to an airway of a subject;
- a gas delivery circuit configured to deliver the pressurized flow of breathable gas from the pressure generator to the airway of the subject;
- a first sensor configured to generate output signals conveying information related to the breathing phase of the subject;
- a second sensor configured to generate output signals conveying information related to the composition of gas at or near the airway of the subject;
- and
- one or more processors configured to execute computer program modules, the computer program modules comprising:
- a control module configured to control the pressure generator to adjust the pressurized flow of breathable gas such that pressure at or near the airway of the subject remains at or above an expiratory pressure level if the output signals generated by the first sensor indicate that the breathing of the subject is in an expiratory phase;
- a therapy pressure module configured to set the expiratory pressure level implemented by the control module during expiratory phases of the breathing of the subject, wherein the therapy pressure module is configured such that during most expiratory phases the expiratory pressure level is set at a predetermined baseline expiratory pressure level, and such that intermittently the expiratory pressure level is lowered below the predetermined baseline expiratory pressure level;
- and
- an exhalation composition module configured to determine a concentration of a gaseous molecular species in gas exhaled from the lungs of the subject, wherein the exhalation composition module is configured such that the determination of the concentration of the gaseous molecular species in gas exhaled from the lungs of the subject is made based on output signals generated by the second sensor during the intermittent expiratory phases for which the expiratory pressure level is lowered below the predetermined baseline expiratory pressure level.
7 more elements
A method of providing pressure support to a subject, the method comprising:
- generating a pressurized flow of breathable gas for delivery to an airway of a subject;
- delivering the pressurized flow of breathable gas to the airway of the subject through a flow path;
- monitoring the breathing phase of the subject;
- collecting samples indicating a concentration of a gaseous molecular species within the flow path;
- adjusting the pressurized flow of breathable gas such that pressure at or near the airway of the subject remains at or above an expiratory pressure level if the breathing of the subject is in an expiratory phase;
- setting the expiratory pressure level implemented during expiratory phases of the breathing of the subject such that during most expiratory phases the expiratory pressure level is set at a predetermined baseline expiratory pressure level, and such that intermittently the expiratory pressure level is lowered below the predetermined baseline expiratory pressure level;
- and
- determining a concentration of the gaseous molecular species in gas exhaled from the lungs of the subject based on samples indicating the concentration of the gaseous molecular species within the flow path during the intermittent expiratory phases for which the expiratory pressure level is lowered below the predetermined baseline expiratory pressure level.
5 more elements
A system configured to provide pressure support to a subject, the system comprising:
- means for generating a pressurized flow of breathable gas for delivery to an airway of a subject;
- means for delivering the pressurized flow of breathable gas to the airway of the subject through a flow path;
- means for monitoring the breathing phase of the subject;
- means for collecting samples indicating a concentration of a gaseous molecular species within the flow path;
- means for adjusting the pressurized flow of breathable gas such that pressure at or near the airway of the subject remains at or above an expiratory pressure level if the breathing of the subject is in an expiratory phase;
- means for setting the expiratory pressure level implemented during expiratory phases of the breathing of the subject such that during most expiratory phases the expiratory pressure level is set at a predetermined baseline expiratory pressure level, and such that during some non-consecutive expiratory phases the expiratory pressure level is lowered below the predetermined baseline expiratory pressure level;
- and
- means for determining a concentration of the gaseous molecular species in gas exhaled from the lungs of the subject based on samples indicating the concentration of the gaseous molecular species within the flow path during the non-consecutive expiratory phases for which the expiratory pressure level is lowered below the predetermined baseline expiratory pressure level.
5 more elements
Dependencies are inferred from the claim text.