Systems and Methods for Electrically Stimulating the Lower Esophageal Sphincter to Treat Gastroesophageal Reflux Disease
AssigneeEndoStim, Inc.
InventorsEdy E. Soffer, Jeffrey Conklin
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Abstract
The present specification describes methods and devices using electrical stimulation to modulate lower esophageal sphincter (LES) pressure. The electrical stimulation may be delivered to the LES via one or more electrodes that is placed in contact with the LES tissue. The methods and devices are useful to treat a number of conditions or disease conditions, including for example, gastroesophageal reflux disease (GERD).
Claims60
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A method of treating GERD in a subject in need thereof, comprising:
- providing an electrical signal;
- and delivering the electrical signal to a portion of a region encompassing said LES, wherein said region comprises the LES, 3 cm above the LES and 3 cm below the LES, to stimulate the LES and to increase the LES pressure, wherein said electrical signal is adapted to cause said LES pressure increase to be maintained for a period after stimulation ceases.
A computer readable medium having computer executable instructions for applying an electrical signal to stimulate the lower esophageal sphincter (LES) to treat a condition or disease condition, comprising:
- instructions to generate and deliver an electrical signal, wherein said electrical signal is adapted to cause said LES pressure increase to be maintained for a period after stimulation ceases;
- and electrodes adapted to be implanted in a portion of a region encompassing the LES, wherein said region comprises the LES, 3 cm above the LES and 3 cm below the LES.
Dependencies are inferred from the claim text.