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US 2012/0232156 A1Published application
Controlled release dosage forms
AssigneeValeant International (Barbados) SRL
InventorSteven E. FRISBEE
Life of this patent
Estimating the term…
Abstract
The invention provides stable controlled release monolithic coating compositions for use in coating pharmaceutical oral dosage forms comprising a polyglycol having a melting point greater than 55° C. and an aqueous dispersion of a neutral ester copolymer lacking functional groups.
Claims14
A controlled release oral dosage form, comprising:
- (1) about 1000 mg of metformin hydrochloride, wherein said oral dosage form further comprises
- (2) means for releasing said metformin hydrochloride to provide a Tmax of said metformin hydrochloride after administration to a patient.
A controlled release oral dosage form, comprising:
- (1) about 1000 mg of metformin hydrochloride, wherein said oral dosage form further comprises
- (2) means for releasing said metformin hydrochloride to provide a Cmax of said metformin hydrochloride after administration to a patient.
A controlled release oral dosage form, comprising:
- (1) about 1000 mg of metformin hydrochloride, wherein said oral dosage form further comprises
- (2) means for releasing said metformin hydrochloride to provide an AUC(0 to t) of said metformin hydrochloride after administration to a patient.
A controlled release oral dosage form, comprising:
- (1) about 1000 mg of metformin hydrochloride, wherein said oral dosage form further comprises
- (2) means for releasing said metformin hydrochloride to provide an AUC(0 to infinity) after administration to a patient.
Dependencies are inferred from the claim text.