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US 2012/0232118 A1Published application
Selective ligands for the dopamine 3 (d3) receptor and methods of using the same
AssigneesUniversity of Kansas, The Regents of the University of Michigan
InventorsShaomeng Wang, Jianyong Chen, Gregory Collins, Beth Levant, James H. Woods
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Abstract
Potent and selective ligands for the dopamine 3 (D3) receptor are disclosed. The D3 receptor ligands have a structural formula: wherein R1 is C1-6 alkyl or C3-6cycloalkyl; or wherein R2 is substituted with one or two halogen(s) or OC1-3alkyl.
Claims19
A compound having a structural formula
- wherein R′ is C1-6 alkyl or C3-6cycloalkyl;
- and
- wherein R2 is
- substituted with one or two halogen(s) or OC1-3alkyl.
1 more element
A compound selected from the group consisting of compounds 33-38 disclosed in Table 1 and compounds 43-47 and 51-53 disclosed in Table 2.
Dependencies are inferred from the claim text.