Methods of treating emesis using growth hormone secretagogues
AssigneeHelsinn Therapeutics (U.S.), Inc.
InventorsWilliam R. Mann, William J. Polvino
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Abstract
The present invention relates to methods of treating or preventing emesis and improving a subject's ASAS score by administering to the subject an effective amount of a growth hormone secretagogue compound or a pharmaceutically acceptable salt, hydrate or solvate thereof.
Claims17
-41. (canceled)
42) A method of treating emesis induced by cancer chemotherapy or post-operative nausea and vomiting in a subject comprising administering to a subject in need of such treatment, via intravenous injection, a treatment effective amount of a compound of structure III, or a pharmaceutically acceptable salt thereof:
43). The method of claim 42, wherein said emesis is post-operative nausea and vomiting.
52) A method of increasing the period of latency in a subject prior to an episode of emesis induced by cancer chemotherapy or post-operative nausea and vomiting, comprising administering to a subject in need of such treatment, via intravenous injection, a treatment effective amount of a compound of structure III, or a pharmaceutically acceptable salt thereof:
55) A method of reducing the number of episodes of retching in a subject induced by cancer chemotherapy or post-operative nausea and vomiting, comprising administering to a subject in need of such treatment, via intravenous injection, a treatment effective amount of a compound of structure III, or a pharmaceutically acceptable salt thereof:
Dependencies are inferred from the claim text.