US 2012/0232008 A1Published application

Plgf-1 in homodimeric form

AssigneesDompe S.p.A., Geymonat S.p.A.

InventorsGaetano D'Anniballe, Franck Martin, Giuseppe Salvia

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Abstract

The present invention relates to a new homodimeric form of recombinant PlGF-1, to a process for its preparation and to compositions containing it.

Claims27

Dependent claims

An isolated Placental Growth Factor (PlGF) homodimer characterized in that the C-terminal cysteine residues of the two monomer proteins forming said homodimer are involved in an intermonomer disulfide bond.

Dependencies are inferred from the claim text.

Facts

Application: 13/394,715Filed 9 Sep 2010
Priority: EP 09169873.89 Sep 2009
Published: 13 Sep 2012
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

C07K 14/515
Growth factors; Growth regulators: angiogenesic factors; Angiogenin
A61P 9/10
Drugs for disorders of the cardiovascular system: for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary…
A61P 17/00
Drugs for dermatological disorders
A61P 17/02
Drugs for dermatological disorders: for treating wounds, ulcers, burns, scars, keloids, or the like

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US 8,962,555 B2Related patent
US 2012/0232008 A1This patent

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